BDBM50048860 CHEMBL3310508
SMILES: [H][C@]12CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@]1([H])CCCCCSSCCCCC[C@]([H])(NC2=O)C(=O)N1
InChI Key: InChIKey=ZQICYEMFUJEREY-NAVOZUGXSA-N
Data: 6 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50048860 (CHEMBL3310508) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rajshahi Curated by ChEMBL | Assay Description Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader | Bioorg Med Chem 22: 3850-5 (2014) Article DOI: 10.1016/j.bmc.2014.06.029 BindingDB Entry DOI: 10.7270/Q23F4R9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50048860 (CHEMBL3310508) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rajshahi Curated by ChEMBL | Assay Description Inhibition of human HDAC4 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader | Bioorg Med Chem 22: 3850-5 (2014) Article DOI: 10.1016/j.bmc.2014.06.029 BindingDB Entry DOI: 10.7270/Q23F4R9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM50048860 (CHEMBL3310508) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rajshahi Curated by ChEMBL | Assay Description Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito... | Bioorg Med Chem 22: 3850-5 (2014) Article DOI: 10.1016/j.bmc.2014.06.029 BindingDB Entry DOI: 10.7270/Q23F4R9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 1 (Homo sapiens (Human)) | BDBM50048860 (CHEMBL3310508) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rajshahi Curated by ChEMBL | Assay Description Inhibition of human HDAC1 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito... | Bioorg Med Chem 22: 3850-5 (2014) Article DOI: 10.1016/j.bmc.2014.06.029 BindingDB Entry DOI: 10.7270/Q23F4R9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 4 (Homo sapiens (Human)) | BDBM50048860 (CHEMBL3310508) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rajshahi Curated by ChEMBL | Assay Description Inhibition of human HDAC4 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader in presence of 0.1 mM dithiothreito... | Bioorg Med Chem 22: 3850-5 (2014) Article DOI: 10.1016/j.bmc.2014.06.029 BindingDB Entry DOI: 10.7270/Q23F4R9P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histone deacetylase 6 (Mus musculus) | BDBM50048860 (CHEMBL3310508) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Rajshahi Curated by ChEMBL | Assay Description Inhibition of mouse HDAC6 using fluorescent substrate Ac-KGLGK(Ac)-MCA after 30 mins by fluorescence plate reader | Bioorg Med Chem 22: 3850-5 (2014) Article DOI: 10.1016/j.bmc.2014.06.029 BindingDB Entry DOI: 10.7270/Q23F4R9P | |||||||||||
More data for this Ligand-Target Pair |