BDBM50049054 (S)-6-(4-Benzylamino-quinazolin-7-yl)-5-methyl-4,5-dihydro-2H-pyridazin-3-one::CHEMBL102807

SMILES: C[C@H]1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1

InChI Key: InChIKey=KJCLPXFGPVCAKL-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50049054 ((S)-6-(4-Benzylamino-quinazolin-7-yl)-5-methyl-4,5...) Show SMILES C[C@H]1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1 |c:6| Show InChI InChI=1S/C20H19N5O/c1-13-9-18(26)24-25-19(13)15-7-8-16-17(10-15)22-12-23-20(16)21-11-14-5-3-2-4-6-14/h2-8,10,12-13H,9,11H2,1H3,(H,24,26)(H,21,22,23)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 5				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50049054 ((S)-6-(4-Benzylamino-quinazolin-7-yl)-5-methyl-4,5...) Show SMILES C[C@H]1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1 |c:6| Show InChI InChI=1S/C20H19N5O/c1-13-9-18(26)24-25-19(13)15-7-8-16-17(10-15)22-12-23-20(16)21-11-14-5-3-2-4-6-14/h2-8,10,12-13H,9,11H2,1H3,(H,24,26)(H,21,22,23)/t13-/m0/s1	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakka Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of bovine arterial Phosphodiesterase 3				J Med Chem 39: 297-303 (1996) Article DOI: 10.1021/jm950197j BindingDB Entry DOI: 10.7270/Q2V125GT
					More data for this Ligand-Target Pair