BDBM50049100 6-Amino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxylic acid amide::CHEMBL111316
SMILES: NC1CCc2[nH]c3ccc(cc3c2C1)C(N)=O
InChI Key: InChIKey=PMQBOSGFSARWCB-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50049100 (6-Amino-6,7,8,9-tetrahydro-5H-carbazole-3-carboxyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity of the compound towards cloned human 5-hydroxytryptamine 1A receptor beta was determined using [3H]-8-OH-DPAT as radioligand | J Med Chem 39: 314-22 (1996) Article DOI: 10.1021/jm950498t BindingDB Entry DOI: 10.7270/Q2DJ5DRK | |||||||||||
More data for this Ligand-Target Pair |