BDBM50049242 5-[1-{4-[2-(Methyl-pyridin-2-yl-amino)-ethoxy]-phenyl}-meth-(Z)-ylidene]-thiazolidine-2,4-dione::CHEMBL297312
SMILES: CN(CCOc1ccc(C=C2SC(O)=NC2=O)cc1)c1ccccn1
InChI Key: InChIKey=HCDYSWMAMRPMST-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Mus musculus) | BDBM50049242 (5-[1-{4-[2-(Methyl-pyridin-2-yl-amino)-ethoxy]-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a |
Glaxo Wellcome Research and Development Curated by ChEMBL | Assay Description In vitro transcriptional activation of Peroxisome proliferator activated receptor gamma (PPAR) expressed in CV-1 cells | J Med Chem 39: 665-8 (1996) Article DOI: 10.1021/jm950395a BindingDB Entry DOI: 10.7270/Q2H9949G | |||||||||||
More data for this Ligand-Target Pair |