BDBM50049246 5-((R)-2-Benzyl-chroman-6-ylmethyl)-thiazolidine-2,4-dione::CHEMBL17669

SMILES: Oc1[nH]c(=O)sc1Cc1ccc2O[C@@H](Cc3ccccc3)CCc2c1

InChI Key: InChIKey=PMUPDWITIYZSPY-MRXNPFEDSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50049246 (5-((R)-2-Benzyl-chroman-6-ylmethyl)-thiazolidine-2...) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc2O[C@@H](Cc3ccccc3)CCc2c1 Show InChI InChI=1S/C20H19NO3S/c22-19-18(25-20(23)21-19)12-14-6-9-17-15(10-14)7-8-16(24-17)11-13-4-2-1-3-5-13/h1-6,9-10,16,22H,7-8,11-12H2,(H,21,23)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation activity at Homo sapiens (human) PPARgamma				Citation and Details Article DOI: 10.1007/s00044-010-9428-9 BindingDB Entry DOI: 10.7270/Q22Z18FD
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Mus musculus)	BDBM50049246 (5-((R)-2-Benzyl-chroman-6-ylmethyl)-thiazolidine-2...) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc2O[C@@H](Cc3ccccc3)CCc2c1 Show InChI InChI=1S/C20H19NO3S/c22-19-18(25-20(23)21-19)12-14-6-9-17-15(10-14)7-8-16(24-17)11-13-4-2-1-3-5-13/h1-6,9-10,16,22H,7-8,11-12H2,(H,21,23)/t16-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a
Glaxo Wellcome Research and Development Curated by ChEMBL					Assay Description In vitro transcriptional activation of Peroxisome proliferator activated receptor gamma (PPAR) expressed in CV-1 cells				J Med Chem 39: 665-8 (1996) Article DOI: 10.1021/jm950395a BindingDB Entry DOI: 10.7270/Q2H9949G
					More data for this Ligand-Target Pair