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BDBM50049247 5-{4-[2-(Benzooxazol-2-yl-methyl-amino)-ethoxy]-phenyl}-thiazolidine-2,4-dione::CHEMBL129562

SMILES: CN(CCOc1ccc(cc1)-c1sc(=O)[nH]c1O)c1nc2ccccc2o1

InChI Key: InChIKey=SFSLYNXWDYDOCR-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049247   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor gamma


(Mus musculus)
BDBM50049247
PNG
(5-{4-[2-(Benzooxazol-2-yl-methyl-amino)-ethoxy]-ph...)
Show SMILES CN(CCOc1ccc(cc1)-c1sc(=O)[nH]c1O)c1nc2ccccc2o1
Show InChI InChI=1S/C19H17N3O4S/c1-22(18-20-14-4-2-3-5-15(14)26-18)10-11-25-13-8-6-12(7-9-13)16-17(23)21-19(24)27-16/h2-9,23H,10-11H2,1H3,(H,21,24)
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MMDB

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Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
In vitro transcriptional activation of Peroxisome proliferator activated receptor gamma (PPAR) expressed in CV-1 cells


J Med Chem 39: 665-8 (1996)


Article DOI: 10.1021/jm950395a
BindingDB Entry DOI: 10.7270/Q2H9949G
More data for this
Ligand-Target Pair