BDBM50049250 CHEMBL306541::[1,3]Thiazinan-(2E)-ylideneamine::[1,3]Thiazinan-(2Z)-ylideneamine

SMILES: NC1=NCCCS1

InChI Key: InChIKey=PQXQEOIFIUJLIE-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50049250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50049250 (CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...) Show SMILES NC1=NCCCS1 |t:1| Show InChI InChI=1S/C4H8N2S/c5-4-6-2-1-3-7-4/h1-3H2,(H2,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human Endothelial nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50049250 (CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...) Show SMILES NC1=NCCCS1 |t:1| Show InChI InChI=1S/C4H8N2S/c5-4-6-2-1-3-7-4/h1-3H2,(H2,5,6)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.				J Med Chem 42: 2227-34 (1999) Article DOI: 10.1021/jm980721x BindingDB Entry DOI: 10.7270/Q23X89CJ
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Homo sapiens (Human))	BDBM50049250 (CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...) Show SMILES NC1=NCCCS1 |t:1| Show InChI InChI=1S/C4H8N2S/c5-4-6-2-1-3-7-4/h1-3H2,(H2,5,6)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human Neuronal nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50049250 (CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...) Show SMILES NC1=NCCCS1 |t:1| Show InChI InChI=1S/C4H8N2S/c5-4-6-2-1-3-7-4/h1-3H2,(H2,5,6)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
G. D. Searle Research and Development Curated by ChEMBL					Assay Description Inhibitory activity against human inducible nitric oxide synthase				J Med Chem 39: 669-72 (1996) Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M
					More data for this Ligand-Target Pair