Found 9 hits for monomerid = 50049255 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Neuronal nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description inhibition of human endothelial constitutive Endothelial nitric oxide synthase (heNOS) |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibition of human Inducible nitric oxide synthase |
J Med Chem 41: 96-101 (1998)
Article DOI: 10.1021/jm9705059 BindingDB Entry DOI: 10.7270/Q2GM86D2 |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibitory activity against human Neuronal nitric oxide synthase (nNOS) |
Bioorg Med Chem Lett 15: 1997-2001 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.067 BindingDB Entry DOI: 10.7270/Q2XK8F3M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity against human Endothelial nitric oxide synthase |
J Med Chem 39: 669-72 (1996)
Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibitory activity against human Inducible nitric oxide synthase (iNOS) |
Bioorg Med Chem Lett 15: 1997-2001 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.067 BindingDB Entry DOI: 10.7270/Q2XK8F3M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity against human inducible nitric oxide synthase |
J Med Chem 39: 669-72 (1996)
Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description Inhibitory activity against human Neuronal nitric oxide synthase |
J Med Chem 39: 669-72 (1996)
Article DOI: 10.1021/jm950766n BindingDB Entry DOI: 10.7270/Q261110M |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50049255
(CHEMBL269058 | PIPERIDIN-2-IMINE | Piperidin-(2E)-...)Show InChI InChI=1S/C5H10N2/c6-5-3-1-2-4-7-5/h1-4H2,(H2,6,7) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Inhibitory activity against human Endothelial nitric oxide synthase (eNOS) |
Bioorg Med Chem Lett 15: 1997-2001 (2005)
Article DOI: 10.1016/j.bmcl.2005.02.067 BindingDB Entry DOI: 10.7270/Q2XK8F3M |
More data for this Ligand-Target Pair | |