BDBM50049442 CHEMBL3356469

SMILES: CC1N2C(COc3cc(c(CC4CNC4)cc23)C(F)(F)F)=NNC1=O

InChI Key: InChIKey=PCJAWCHEJIWAOI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049442   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50049442 (CHEMBL3356469) Show SMILES CC1N2C(COc3cc(c(CC4CNC4)cc23)C(F)(F)F)=NNC1=O |c:23| Show InChI InChI=1S/C16H17F3N4O2/c1-8-15(24)22-21-14-7-25-13-4-11(16(17,18)19)10(2-9-5-20-6-9)3-12(13)23(8)14/h3-4,8-9,20H,2,5-7H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...				J Med Chem 58: 222-36 (2015) Article DOI: 10.1021/jm500669m BindingDB Entry DOI: 10.7270/Q22F7Q2Z
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50049442 (CHEMBL3356469) Show SMILES CC1N2C(COc3cc(c(CC4CNC4)cc23)C(F)(F)F)=NNC1=O |c:23| Show InChI InChI=1S/C16H17F3N4O2/c1-8-15(24)22-21-14-7-25-13-4-11(16(17,18)19)10(2-9-5-20-6-9)3-12(13)23(8)14/h3-4,8-9,20H,2,5-7H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCalpha expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...				J Med Chem 58: 222-36 (2015) Article DOI: 10.1021/jm500669m BindingDB Entry DOI: 10.7270/Q22F7Q2Z
					More data for this Ligand-Target Pair