BDBM50049450 CHEMBL3356457

SMILES: O=C(Nc1ccc2OCC3=NNC(=O)CN3c2c1)C1CCNC1

InChI Key: InChIKey=QEDYWIQHMHMSCN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50049450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50049450 (CHEMBL3356457) Show SMILES O=C(Nc1ccc2OCC3=NNC(=O)CN3c2c1)C1CCNC1 |t:9| Show InChI InChI=1S/C15H17N5O3/c21-14-7-20-11-5-10(17-15(22)9-3-4-16-6-9)1-2-12(11)23-8-13(20)18-19-14/h1-2,5,9,16H,3-4,6-8H2,(H,17,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...				J Med Chem 58: 222-36 (2015) Article DOI: 10.1021/jm500669m BindingDB Entry DOI: 10.7270/Q22F7Q2Z
					More data for this Ligand-Target Pair