BDBM50049708 CHEMBL148::IMIPENEM

SMILES: C[C@@H](O)[C@@H]1[C@H]2CC(SCCN=CN)=C(N2C1=O)C(O)=O

InChI Key: InChIKey=ZSKVGTPCRGIANV-ZXFLCMHBSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50049708   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PER-2 beta-lactamase (Citrobacter freundii)	BDBM50049708 (CHEMBL148 | IMIPENEM) Show SMILES C[C@@H](O)[C@@H]1[C@H]2CC(SCCN=CN)=C(N2C1=O)C(O)=O |r,w:11.11,c:12| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Buenos Aires Curated by ChEMBL					Assay Description Inhibition of Citrobacter freundii PER2 beta lactamase				Antimicrob Agents Chemother 51: 2359-65 (2007) Article DOI: 10.1128/AAC.01395-06 BindingDB Entry DOI: 10.7270/Q24X57J4
					More data for this Ligand-Target Pair
Beta-lactamase GES-13 (Pseudomonas aeruginosa)	BDBM50049708 (CHEMBL148 | IMIPENEM) Show SMILES C[C@@H](O)[C@@H]1[C@H]2CC(SCCN=CN)=C(N2C1=O)C(O)=O |r,w:11.11,c:12| Show InChI InChI=1S/C12H17N3O4S/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19)/t6-,7-,9-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Hellenic Pasteur Institute Curated by ChEMBL					Assay Description Inhibition of Pseudomonas aeruginosa GES-13 beta lactamase				Antimicrob Agents Chemother 54: 1331-3 (2010) Article DOI: 10.1128/AAC.01561-09 BindingDB Entry DOI: 10.7270/Q29C6XN5
					More data for this Ligand-Target Pair