BDBM50050156 (S)-1-[(S)-2-((2S,3S)-2-Mercapto-3-methyl-pentanoylamino)-3-methyl-butyryl]-pyrrolidine-2-carboxylic acid::CHEMBL20182
SMILES: CC[C@H](C)[C@H](S)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(O)=O
InChI Key: InChIKey=JBSHPQOWHDANOU-CYDGBPFRSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Rattus norvegicus) | BDBM50050156 ((S)-1-[(S)-2-((2S,3S)-2-Mercapto-3-methyl-pentanoy...) | KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.580 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity against angiotensin I converting enzyme | J Med Chem 39: 1210-9 (1996) Article DOI: 10.1021/jm950590p BindingDB Entry DOI: 10.7270/Q2DF6RWV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neprilysin (Oryctolagus cuniculus (rabbit)) | BDBM50050156 ((S)-1-[(S)-2-((2S,3S)-2-Mercapto-3-methyl-pentanoy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
INSERM Curated by ChEMBL | Assay Description Inhibitory activity was tested against neutral endopeptidase | J Med Chem 39: 1210-9 (1996) Article DOI: 10.1021/jm950590p BindingDB Entry DOI: 10.7270/Q2DF6RWV | |||||||||||
More data for this Ligand-Target Pair |