BDBM50050175 4-{3-[3-(4-Iodo-phenyl)-propoxy]-propyl}-1H-imidazole::CHEMBL20686

SMILES: Ic1ccc(CCCOCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=CEQTUMPCLZAZJB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050175 (4-{3-[3-(4-Iodo-phenyl)-propoxy]-propyl}-1H-imidaz...) Show SMILES Ic1ccc(CCCOCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H19IN2O/c16-14-7-5-13(6-8-14)3-1-9-19-10-2-4-15-11-17-12-18-15/h5-8,11-12H,1-4,9-10H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Binding affinity towards Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050175 (4-{3-[3-(4-Iodo-phenyl)-propoxy]-propyl}-1H-imidaz...) Show SMILES Ic1ccc(CCCOCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H19IN2O/c16-14-7-5-13(6-8-14)3-1-9-19-10-2-4-15-11-17-12-18-15/h5-8,11-12H,1-4,9-10H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050175 (4-{3-[3-(4-Iodo-phenyl)-propoxy]-propyl}-1H-imidaz...) Show SMILES Ic1ccc(CCCOCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C15H19IN2O/c16-14-7-5-13(6-8-14)3-1-9-19-10-2-4-15-11-17-12-18-15/h5-8,11-12H,1-4,9-10H2,(H,17,18)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair