BDBM50050181 4-[3-(4-Iodo-phenoxy)-propyl]-1H-imidazole::CHEMBL21230

SMILES: Ic1ccc(OCCCc2cnc[nH]2)cc1

InChI Key: InChIKey=HLDXQIZPYLLWBO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050181 (4-[3-(4-Iodo-phenoxy)-propyl]-1H-imidazole | CHEMB...) Show SMILES Ic1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H13IN2O/c13-10-3-5-12(6-4-10)16-7-1-2-11-8-14-9-15-11/h3-6,8-9H,1-2,7H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description Binding affinity towards Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050181 (4-[3-(4-Iodo-phenoxy)-propyl]-1H-imidazole | CHEMB...) Show SMILES Ic1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H13IN2O/c13-10-3-5-12(6-4-10)16-7-1-2-11-8-14-9-15-11/h3-6,8-9H,1-2,7H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50050181 (4-[3-(4-Iodo-phenoxy)-propyl]-1H-imidazole | CHEMB...) Show SMILES Ic1ccc(OCCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C12H13IN2O/c13-10-3-5-12(6-4-10)16-7-1-2-11-8-14-9-15-11/h3-6,8-9H,1-2,7H2,(H,14,15)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Freie Universität Berlin Curated by ChEMBL					Assay Description In vitro antagonistic activity tested against Histamine H3 receptor on synaptosomes from rat cerebral cortex				J Med Chem 39: 1220-6 (1996) Article DOI: 10.1021/jm9504767 BindingDB Entry DOI: 10.7270/Q28K7855
					More data for this Ligand-Target Pair