BDBM50050433 CHEMBL3186489

SMILES: O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1

InChI Key: InChIKey=SDLHRUDTCAGBLQ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50050433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM50050433 (CHEMBL3186489) Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1 Show InChI InChI=1S/C20H16N2O2/c23-19(15-8-3-1-4-9-15)21-17-12-7-13-18(14-17)22-20(24)16-10-5-2-6-11-16/h1-14H,(H,21,23)(H,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM50050433 (CHEMBL3186489) Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1 Show InChI InChI=1S/C20H16N2O2/c23-19(15-8-3-1-4-9-15)21-17-12-7-13-18(14-17)22-20(24)16-10-5-2-6-11-16/h1-14H,(H,21,23)(H,22,24)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-1 (unknown origin) by parental cell based thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM50050433 (CHEMBL3186489) Show SMILES O=C(Nc1cccc(NC(=O)c2ccccc2)c1)c1ccccc1 Show InChI InChI=1S/C20H16N2O2/c23-19(15-8-3-1-4-9-15)21-17-12-7-13-18(14-17)22-20(24)16-10-5-2-6-11-16/h1-14H,(H,21,23)(H,22,24)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair