BDBM50050435 CHEMBL3183938

SMILES: COc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1

InChI Key: InChIKey=OZBQDKIFIYHBDV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM50050435 (CHEMBL3183938) Show SMILES COc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H18N2O3/c1-26-19-12-5-9-16(13-19)21(25)23-18-11-6-10-17(14-18)22-20(24)15-7-3-2-4-8-15/h2-14H,1H3,(H,22,24)(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM50050435 (CHEMBL3183938) Show SMILES COc1cccc(c1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C21H18N2O3/c1-26-19-12-5-9-16(13-19)21(25)23-18-11-6-10-17(14-18)22-20(24)15-7-3-2-4-8-15/h2-14H,1H3,(H,22,24)(H,23,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair