BDBM50050446 CHEMBL3184653

SMILES: CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1

InChI Key: InChIKey=SRNCQMFKRVHZHM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium channel subfamily K member 9 (Homo sapiens (Human))	BDBM50050446 (CHEMBL3184653) Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C22H21N3O2/c1-25(2)20-13-11-17(12-14-20)22(27)24-19-10-6-9-18(15-19)23-21(26)16-7-4-3-5-8-16/h3-15H,1-2H3,(H,23,26)(H,24,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair
Potassium channel protein TASK-1 (Homo sapiens (Human))	BDBM50050446 (CHEMBL3184653) Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 Show InChI InChI=1S/C22H21N3O2/c1-25(2)20-13-11-17(12-14-20)22(27)24-19-10-6-9-18(15-19)23-21(26)16-7-4-3-5-8-16/h3-15H,1-2H3,(H,23,26)(H,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay				Bioorg Med Chem Lett 24: 3968-73 (2014) Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487
					More data for this Ligand-Target Pair