BDBM50050481 10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-trien-4-ol::CHEMBL58059
SMILES: CNCC12Cc3ccc(O)cc3C(C)(CCC1N)C2
InChI Key: InChIKey=OIWAOFDWJNPNPF-UHFFFAOYSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig)) | BDBM50050481 (10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding site | J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu opioid receptor (CALF) | BDBM50050481 (10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 91.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding site | J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM50050481 (10-Amino-1-methyl-9-methylaminomethyl-tricyclo[7.3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 459 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute Curated by ChEMBL | Assay Description Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding site | J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8 | |||||||||||
More data for this Ligand-Target Pair |