BDBM50050484 10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0*2,7*]trideca-2,4,6-trien-4-ol::CHEMBL409026

SMILES: CC12CCC(N)C(CO)(Cc3ccc(O)cc13)C2

InChI Key: InChIKey=TYULFMDMDFGHME-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50050484   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu opioid receptor (CALF)	BDBM50050484 (10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...) Show SMILES CC12CCC(N)C(CO)(Cc3ccc(O)cc13)C2 |THB:15:16:17:4.2.3,5:4:17:16.10.9| Show InChI InChI=1S/C15H21NO2/c1-14-5-4-13(16)15(8-14,9-17)7-10-2-3-11(18)6-12(10)14/h2-3,6,13,17-18H,4-5,7-9,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair
Mu opioid receptor (CALF)	BDBM50050484 (10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...) Show SMILES CC12CCC(N)C(CO)(Cc3ccc(O)cc13)C2 |THB:15:16:17:4.2.3,5:4:17:16.10.9| Show InChI InChI=1S/C15H21NO2/c1-14-5-4-13(16)15(8-14,9-17)7-10-2-3-11(18)6-12(10)14/h2-3,6,13,17-18H,4-5,7-9,16H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 0.8 nM [3H]- DAMGO at Opioid receptor mu 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50050484 (10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...) Show SMILES CC12CCC(N)C(CO)(Cc3ccc(O)cc13)C2 |THB:15:16:17:4.2.3,5:4:17:16.10.9| Show InChI InChI=1S/C15H21NO2/c1-14-5-4-13(16)15(8-14,9-17)7-10-2-3-11(18)6-12(10)14/h2-3,6,13,17-18H,4-5,7-9,16H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]U69,593 at Opioid receptor kappa 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50050484 (10-Amino-9-hydroxymethyl-1-methyl-tricyclo[7.3.1.0...) Show SMILES CC12CCC(N)C(CO)(Cc3ccc(O)cc13)C2 |THB:15:16:17:4.2.3,5:4:17:16.10.9| Show InChI InChI=1S/C15H21NO2/c1-14-5-4-13(16)15(8-14,9-17)7-10-2-3-11(18)6-12(10)14/h2-3,6,13,17-18H,4-5,7-9,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Activity of the compound was evaluated by inhibition of the binding of 1 nM [3H]-DPDPE at Opioid receptor delta 1 binding site				J Med Chem 39: 1956-66 (1996) Article DOI: 10.1021/jm950817g BindingDB Entry DOI: 10.7270/Q2CC0ZR8
					More data for this Ligand-Target Pair