BDBM50050532 1-[2-[2-oxo-(5S)-dihydro-2H-5-pyrrolylcarboxamido]-3-phenyl-(2S)-propanoyl]-(2S)-tetrahydro-1H-2-pyrrolecarboxamide::CHEMBL36631

SMILES: NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCC(=O)N1

InChI Key: InChIKey=ZETOYWKJNIJFCR-KKUMJFAQSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyrotropin-releasing hormone receptor (MOUSE)	BDBM50050532 (1-[2-[2-oxo-(5S)-dihydro-2H-5-pyrrolylcarboxamido]...) Show SMILES NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCC(=O)N1 Show InChI InChI=1S/C19H24N4O4/c20-17(25)15-7-4-10-23(15)19(27)14(11-12-5-2-1-3-6-12)22-18(26)13-8-9-16(24)21-13/h1-3,5-6,13-15H,4,7-11H2,(H2,20,25)(H,21,24)(H,22,26)/t13-,14-,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Binding affinity against TRH-R receptor in AtT-20 mouse pituitary tumor cells				J Med Chem 39: 1571-4 (1996) Article DOI: 10.1021/jm960053k BindingDB Entry DOI: 10.7270/Q2H70GGR
					More data for this Ligand-Target Pair
Thyrotropin-releasing hormone receptor (MOUSE)	BDBM50050532 (1-[2-[2-oxo-(5S)-dihydro-2H-5-pyrrolylcarboxamido]...) Show SMILES NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCC(=O)N1 Show InChI InChI=1S/C19H24N4O4/c20-17(25)15-7-4-10-23(15)19(27)14(11-12-5-2-1-3-6-12)22-18(26)13-8-9-16(24)21-13/h1-3,5-6,13-15H,4,7-11H2,(H2,20,25)(H,21,24)(H,22,26)/t13-,14-,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Effective concentration required to activate TRH-R receptor in AtT-20 mouse pituitary tumor cells				J Med Chem 39: 1571-4 (1996) Article DOI: 10.1021/jm960053k BindingDB Entry DOI: 10.7270/Q2H70GGR
					More data for this Ligand-Target Pair