Found 7 hits for monomerid = 50050539 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Potassium channel protein TASK-1
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of TASK-1 (unknown origin) expressed in CHO cells by thallium flux assay |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |
KCNQ (Kv7) potassium channel
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of KCNQ2 (unknown origin) |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of human ERG |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |
Potassium channel subfamily K member 9
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of TASK-3 (unknown origin) expressed in CHO cells by thallium flux assay |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |
Potassium channel protein TASK-1
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of TASK-1 (unknown origin) expressed in CHO cells by QPatch assay |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |
Potassium channel subfamily K member 9
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of TASK-3 (unknown origin) expressed in HEK293 cells by QPatch assay |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |
Inward rectifier potassium channel 2
(Homo sapiens (Human)) | BDBM50050539
(CHEMBL3187891)Show InChI InChI=1S/C20H17N3O2/c1-14-4-2-5-16(12-14)20(25)23-18-7-3-6-17(13-18)22-19(24)15-8-10-21-11-9-15/h2-13H,1H3,(H,22,24)(H,23,25) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kansas Specialized Chemistry Center
Curated by ChEMBL
| Assay Description Inhibition of Kir2.1 (unknown origin) |
Bioorg Med Chem Lett 24: 3968-73 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.032 BindingDB Entry DOI: 10.7270/Q2805487 |
More data for this Ligand-Target Pair | |