BDBM50050850 CHEMBL3318024

SMILES: CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1

InChI Key: InChIKey=WWUXHXQJFWXACS-UHFFFAOYSA-N

Data: 8 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50050850   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of PIM1 (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Homeodomain-interacting protein kinase 1 (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of HIPK1 (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	624	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of Aurora B (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Yes (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of YES (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of TrkA (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of c-Abl (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50050850 (CHEMBL3318024) Show SMILES CCNC(=O)Nc1ccc2ncc(cc2n1)-c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C19H20N4O3/c1-4-20-19(24)23-18-8-6-14-15(22-18)9-13(11-21-14)12-5-7-16(25-2)17(10-12)26-3/h5-11H,4H2,1-3H3,(H2,20,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	742	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Nantes Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin)				Bioorg Med Chem Lett 24: 3748-52 (2014) Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z
					More data for this Ligand-Target Pair