BDBM50050856 CHEMBL3318009
SMILES: COc1ccc(cc1OC)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1
InChI Key: InChIKey=CYDLLRAWQLOGHD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50050856 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050856
(CHEMBL3318009)Show SMILES COc1ccc(cc1OC)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-15-8-9-22-16-10-14(12-23-19(15)16)13-6-7-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,22,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 714 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078
BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050856
(CHEMBL3318009)Show SMILES COc1ccc(cc1OC)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1 Show InChI InChI=1S/C21H24N4O3/c1-21(2,3)25-20(26)24-15-8-9-22-16-10-14(12-23-19(15)16)13-6-7-17(27-4)18(11-13)28-5/h6-12H,1-5H3,(H2,22,24,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description
Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078
BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this
Ligand-Target Pair | |
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