BDBM50050858 CHEMBL3318032
SMILES: Cn1cc(cn1)-c1cnc2c(NC(=O)NC(C)(C)C)ccnc2c1
InChI Key: InChIKey=INYFZUAYEBZZFA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50050858 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aurora kinase B
(Homo sapiens (Human)) | BDBM50050858
(CHEMBL3318032)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-13-5-6-18-14-7-11(8-19-15(13)14)12-9-20-23(4)10-12/h5-10H,1-4H3,(H2,18,21,22,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of Aurora B (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 1
(Homo sapiens (Human)) | BDBM50050858
(CHEMBL3318032)Show InChI InChI=1S/C17H20N6O/c1-17(2,3)22-16(24)21-13-5-6-18-14-7-11(8-19-15(13)14)12-9-20-23(4)10-12/h5-10H,1-4H3,(H2,18,21,22,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Nantes
Curated by ChEMBL
| Assay Description Inhibition of ERK2 (unknown origin) |
Bioorg Med Chem Lett 24: 3748-52 (2014)
Article DOI: 10.1016/j.bmcl.2014.06.078 BindingDB Entry DOI: 10.7270/Q270832Z |
More data for this Ligand-Target Pair | |