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SMILES: COc1cc2nc(nc(NCCCCCN(C)C)c2cc1OC)N1CCCC1

InChI Key: InChIKey=PCZVELLZUFJMOM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051122   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
N-lysine methyltransferase KMT5A


(Homo sapiens (Human))		BDBM50051122
PNG
(CHEMBL3318290)
Show SMILES COc1cc2nc(nc(NCCCCCN(C)C)c2cc1OC)N1CCCC1
Show InChI InChI=1S/C21H33N5O2/c1-25(2)11-7-5-6-10-22-20-16-14-18(27-3)19(28-4)15-17(16)23-21(24-20)26-12-8-9-13-26/h14-15H,5-13H2,1-4H3,(H,22,23,24)
PDB

UniProtKB/SwissProt

antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 7.90E+3n/an/an/an/an/an/a



University of North Carolina at Chapel Hill

Curated by ChEMBL


Assay Description
Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...

J Med Chem 57: 6822-33 (2014)


Article DOI: 10.1021/jm500871s
BindingDB Entry DOI: 10.7270/Q2J9681Q
More data for this
Ligand-Target Pair