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BDBM50051302 (3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine::CHEMBL311129

SMILES: Cc1c([nH]c2ncnc(Nc3cccc(Cl)c3)c12)-c1ccccc1

InChI Key: InChIKey=SUHVLNRNLVTOCF-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50051302
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50051302 ((3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Protein kinase C alpha				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
CIBA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50051302 ((3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against epidermal growth factor receptor				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
CIBA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50051302 ((3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tyrosine kinase c-Src				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
CIBA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL (Homo sapiens (Human))	BDBM50051302 ((3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tyrosine kinase v-Abl				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
CIBA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50051302 ((3-Chloro-phenyl)-(5-methyl-6-phenyl-7H-pyrrolo[2,...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-R				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
CIBA Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair