BDBM50051312 (3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine::CHEMBL74722

SMILES: Cc1[nH]c2ncnc(Nc3cccc(Br)c3)c2c1C

InChI Key: InChIKey=FCNOOCZWZIUGIT-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50051312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50051312 ((3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]py...) Show SMILES Cc1[nH]c2ncnc(Nc3cccc(Br)c3)c2c1C Show InChI InChI=1S/C14H13BrN4/c1-8-9(2)18-13-12(8)14(17-7-16-13)19-11-5-3-4-10(15)6-11/h3-7H,1-2H3,(H2,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of Protein kinase C alpha				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50051312 ((3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]py...) Show SMILES Cc1[nH]c2ncnc(Nc3cccc(Br)c3)c2c1C Show InChI InChI=1S/C14H13BrN4/c1-8-9(2)18-13-12(8)14(17-7-16-13)19-11-5-3-4-10(15)6-11/h3-7H,1-2H3,(H2,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of EGF-stimulated tyrosine phosphorylation in A431 cells expressing EGF-R				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL (Homo sapiens (Human))	BDBM50051312 ((3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]py...) Show SMILES Cc1[nH]c2ncnc(Nc3cccc(Br)c3)c2c1C Show InChI InChI=1S/C14H13BrN4/c1-8-9(2)18-13-12(8)14(17-7-16-13)19-11-5-3-4-10(15)6-11/h3-7H,1-2H3,(H2,16,17,18,19)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tyrosine kinase v-Abl				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50051312 ((3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]py...) Show SMILES Cc1[nH]c2ncnc(Nc3cccc(Br)c3)c2c1C Show InChI InChI=1S/C14H13BrN4/c1-8-9(2)18-13-12(8)14(17-7-16-13)19-11-5-3-4-10(15)6-11/h3-7H,1-2H3,(H2,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of tyrosine kinase c-Src				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50051312 ((3-Bromo-phenyl)-(5,6-dimethyl-7H-pyrrolo[2,3-d]py...) Show SMILES Cc1[nH]c2ncnc(Nc3cccc(Br)c3)c2c1C Show InChI InChI=1S/C14H13BrN4/c1-8-9(2)18-13-12(8)14(17-7-16-13)19-11-5-3-4-10(15)6-11/h3-7H,1-2H3,(H2,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
CIBA Pharmaceuticals Curated by ChEMBL					Assay Description In vitro inhibitory activity against epidermal growth factor receptor				J Med Chem 39: 2285-92 (1996) Article DOI: 10.1021/jm960118j BindingDB Entry DOI: 10.7270/Q2J1028B
					More data for this Ligand-Target Pair