BDBM50051767 (1Z,N'E)-N'-((5-(propylamino)pyridin-2-yl)methylene)carbamohydrazonothioic acid::CHEMBL86963

SMILES: CCCNc1ccc(C=NNC(N)=S)nc1

InChI Key: InChIKey=QKRCJKBFPOAADI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribonucleoside-diphosphate reductase subunit M2 (Homo sapiens (Human))	BDBM50051767 ((1Z,N'E)-N'-((5-(propylamino)pyridin-2-yl)methylen...) Show SMILES CCCNc1ccc(C=NNC(N)=S)nc1 |w:8.7| Show InChI InChI=1S/C10H15N5S/c1-2-5-12-8-3-4-9(13-6-8)7-14-15-10(11)16/h3-4,6-7,12H,2,5H2,1H3,(H3,11,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Inhibitory activity against CDP reductase.				J Med Chem 39: 2586-93 (1996) Article DOI: 10.1021/jm9600454 BindingDB Entry DOI: 10.7270/Q2KS6QN9
					More data for this Ligand-Target Pair