new BindingDB logo
myBDB logout

BDBM50051771 (1Z,N'E)-N'-((3,5-diaminopyridin-2-yl)methylene)carbamohydrazonothioic acid::CHEMBL86910

SMILES: NC(=S)NN=Cc1ncc(N)cc1N

InChI Key: InChIKey=CFOZYZUWMBJGOV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50051771   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribonucleoside-diphosphate reductase subunit M2


(Homo sapiens (Human))
BDBM50051771
PNG
((1Z,N'E)-N'-((3,5-diaminopyridin-2-yl)methylene)ca...)
Show SMILES NC(=S)NN=Cc1ncc(N)cc1N |w:4.3|
Show InChI InChI=1S/C7H10N6S/c8-4-1-5(9)6(11-2-4)3-12-13-7(10)14/h1-3H,8-9H2,(H3,10,13,14)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibitory activity against CDP reductase.


J Med Chem 39: 2586-93 (1996)


Article DOI: 10.1021/jm9600454
BindingDB Entry DOI: 10.7270/Q2KS6QN9
More data for this
Ligand-Target Pair