BDBM50051778 (2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylamino)-acetyl]-5-o-tolyl-pyrrolidine-2-carboxylic acid::CHEMBL86475

SMILES: Cc1ccccc1[C@H]1CC[C@H](N1C(=O)CNC(=O)[C@@H](S)Cc1ccccc1)C(O)=O

InChI Key: InChIKey=WRLCVWPYCWOFQU-AABGKKOBSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051778   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50051778 ((2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylami...) Show SMILES Cc1ccccc1[C@H]1CC[C@H](N1C(=O)CNC(=O)[C@@H](S)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C23H26N2O4S/c1-15-7-5-6-10-17(15)18-11-12-19(23(28)29)25(18)21(26)14-24-22(27)20(30)13-16-8-3-2-4-9-16/h2-10,18-20,30H,11-14H2,1H3,(H,24,27)(H,28,29)/t18-,19+,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description In vitro inhibition of neutral endopeptidase				J Med Chem 39: 2594-608 (1996) Article DOI: 10.1021/jm950783c BindingDB Entry DOI: 10.7270/Q25B0353
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50051778 ((2S,5R)-1-[2-((S)-2-Mercapto-3-phenyl-propionylami...) Show SMILES Cc1ccccc1[C@H]1CC[C@H](N1C(=O)CNC(=O)[C@@H](S)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C23H26N2O4S/c1-15-7-5-6-10-17(15)18-11-12-19(23(28)29)25(18)21(26)14-24-22(27)20(30)13-16-8-3-2-4-9-16/h2-10,18-20,30H,11-14H2,1H3,(H,24,27)(H,28,29)/t18-,19+,20+/m1/s1	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description In vitro inhibition of rat angiotensin I converting enzyme				J Med Chem 39: 2594-608 (1996) Article DOI: 10.1021/jm950783c BindingDB Entry DOI: 10.7270/Q25B0353
					More data for this Ligand-Target Pair