BDBM50051799 (2S,5R)-1-{2-[(S)-2-Mercapto-3-(4-methoxy-phenyl)-propionylamino]-acetyl}-5-(2-methoxy-phenyl)-pyrrolidine-2-carboxylic acid::CHEMBL313764

SMILES: COc1ccc(C[C@H](S)C(=O)NCC(=O)N2[C@@H](CC[C@@H]2c2ccccc2OC)C(O)=O)cc1

InChI Key: InChIKey=RNXQKWJGTTWJCQ-DYXWJJEUSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50051799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Oryctolagus cuniculus (rabbit))	BDBM50051799 ((2S,5R)-1-{2-[(S)-2-Mercapto-3-(4-methoxy-phenyl)-...) Show SMILES COc1ccc(C[C@H](S)C(=O)NCC(=O)N2[C@@H](CC[C@@H]2c2ccccc2OC)C(O)=O)cc1 Show InChI InChI=1S/C24H28N2O6S/c1-31-16-9-7-15(8-10-16)13-21(33)23(28)25-14-22(27)26-18(11-12-19(26)24(29)30)17-5-3-4-6-20(17)32-2/h3-10,18-19,21,33H,11-14H2,1-2H3,(H,25,28)(H,29,30)/t18-,19+,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description In vitro inhibition of neutral endopeptidase				J Med Chem 39: 2594-608 (1996) Article DOI: 10.1021/jm950783c BindingDB Entry DOI: 10.7270/Q25B0353
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Rattus norvegicus)	BDBM50051799 ((2S,5R)-1-{2-[(S)-2-Mercapto-3-(4-methoxy-phenyl)-...) Show SMILES COc1ccc(C[C@H](S)C(=O)NCC(=O)N2[C@@H](CC[C@@H]2c2ccccc2OC)C(O)=O)cc1 Show InChI InChI=1S/C24H28N2O6S/c1-31-16-9-7-15(8-10-16)13-21(33)23(28)25-14-22(27)26-18(11-12-19(26)24(29)30)17-5-3-4-6-20(17)32-2/h3-10,18-19,21,33H,11-14H2,1-2H3,(H,25,28)(H,29,30)/t18-,19+,21+/m1/s1	KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description In vitro inhibition of rat angiotensin I converting enzyme				J Med Chem 39: 2594-608 (1996) Article DOI: 10.1021/jm950783c BindingDB Entry DOI: 10.7270/Q25B0353
					More data for this Ligand-Target Pair