BDBM50051956 2-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol::CHEMBL37844
SMILES: CCCN(CCC)[C@H]1C[C@@H]1c1ccccc1O
InChI Key: InChIKey=LARFBOKVMNMLSW-KGLIPLIRSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HTR5A (RAT) | BDBM50051956 (2-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of specific [3H]-OH-DPAT binding at 5-hydroxytryptamine 1A receptor in rat hippocampal membranes | Bioorg Med Chem Lett 6: 415-420 (1996) Article DOI: 10.1016/0960-894X(96)00045-5 BindingDB Entry DOI: 10.7270/Q20R9PD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50051956 (2-((1R,2S)-2-Dipropylamino-cyclopropyl)-phenol | C...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description In vitro binding affinity of compound towards 5-hydroxytryptamine 1A receptor was determined using [3H]8-OH-DPAT as radioligand; range=100-230 | J Med Chem 39: 1485-93 (1996) Article DOI: 10.1021/jm9507136 BindingDB Entry DOI: 10.7270/Q2RR1ZWN | |||||||||||
More data for this Ligand-Target Pair |