BDBM50052059 5-Methyl-5-phenyl-6-thia-10b-aza-benzo[e]azulen-4-one::CHEMBL316094

SMILES: CC1(Sc2ccccc2-n2cccc2C1=O)c1ccccc1

InChI Key: InChIKey=SSDOAOBSEPIANH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50052059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50052059 (5-Methyl-5-phenyl-6-thia-10b-aza-benzo[e]azulen-4-...) Show SMILES CC1(Sc2ccccc2-n2cccc2C1=O)c1ccccc1 Show InChI InChI=1S/C19H15NOS/c1-19(14-8-3-2-4-9-14)18(21)16-11-7-13-20(16)15-10-5-6-12-17(15)22-19/h2-13H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Experimental Botany ASCR & Palack£ University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase				Bioorg Med Chem 23: 5247-63 (2015) Article DOI: 10.1016/j.bmc.2015.06.016 BindingDB Entry DOI: 10.7270/Q20P131K
					More data for this Ligand-Target Pair
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50052059 (5-Methyl-5-phenyl-6-thia-10b-aza-benzo[e]azulen-4-...) Show SMILES CC1(Sc2ccccc2-n2cccc2C1=O)c1ccccc1 Show InChI InChI=1S/C19H15NOS/c1-19(14-8-3-2-4-9-14)18(21)16-11-7-13-20(16)15-10-5-6-12-17(15)22-19/h2-13H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universitá di Siena Curated by ChEMBL					Assay Description Compound was tested for Inhibition of HIV-1 RT activity.				J Med Chem 39: 2672-80 (1996) Article DOI: 10.1021/jm950702c BindingDB Entry DOI: 10.7270/Q21R6PM4
					More data for this Ligand-Target Pair