BDBM50052390 4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester::CHEMBL99744

SMILES: CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC

InChI Key: InChIKey=YAFCSIDWUVPZTD-UHFFFAOYSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50052390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50052390 (4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dica...) Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC |c:5,t:8| Show InChI InChI=1S/C14H21NO4/c1-6-10-11(13(16)18-5)8(3)15-9(4)12(10)14(17)19-7-2/h10-11H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against adenosine A1 receptor in rat cerebral cortex membrane by radioligand binding assay using [3H](R)-PIA.				J Med Chem 39: 4667-75 (1996) Article DOI: 10.1021/jm960457c BindingDB Entry DOI: 10.7270/Q2VQ33BG
					More data for this Ligand-Target Pair
Adenosine receptor A1 (Rattus norvegicus (rat))	BDBM50052390 (4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dica...) Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC |c:5,t:8| Show InChI InChI=1S/C14H21NO4/c1-6-10-11(13(16)18-5)8(3)15-9(4)12(10)14(17)19-7-2/h10-11H,6-7H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Displacement of [3H](R)-PIA binding to Adenosine A1 receptor in rat brain membranes				J Med Chem 39: 2980-9 (1996) Article DOI: 10.1021/jm9600205 BindingDB Entry DOI: 10.7270/Q2833SQ6
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50052390 (4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dica...) Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC |c:5,t:8| Show InChI InChI=1S/C14H21NO4/c1-6-10-11(13(16)18-5)8(3)15-9(4)12(10)14(17)19-7-2/h10-11H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Displacement of [3H]-CGS- 21680 from Adenosine A2A receptor of rat striatal membrane				J Med Chem 39: 4667-75 (1996) Article DOI: 10.1021/jm960457c BindingDB Entry DOI: 10.7270/Q2VQ33BG
					More data for this Ligand-Target Pair
Adenosine Receptors A2a (A2a) (Rattus norvegicus (rat))	BDBM50052390 (4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dica...) Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC |c:5,t:8| Show InChI InChI=1S/C14H21NO4/c1-6-10-11(13(16)18-5)8(3)15-9(4)12(10)14(17)19-7-2/h10-11H,6-7H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Displacement of [3H]-CGS- 21680 binding to Adenosine A2A receptor in rat striatal membranes				J Med Chem 39: 2980-9 (1996) Article DOI: 10.1021/jm9600205 BindingDB Entry DOI: 10.7270/Q2833SQ6
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50052390 (4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dica...) Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC |c:5,t:8| Show InChI InChI=1S/C14H21NO4/c1-6-10-11(13(16)18-5)8(3)15-9(4)12(10)14(17)19-7-2/h10-11H,6-7H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Binding affinity against cloned human adenosine A3 receptor by radioligand binding assay using [125I]-AB-MECA.				J Med Chem 39: 4667-75 (1996) Article DOI: 10.1021/jm960457c BindingDB Entry DOI: 10.7270/Q2VQ33BG
					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50052390 (4-Ethyl-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dica...) Show SMILES CCOC(=O)C1=C(C)N=C(C)C(C1CC)C(=O)OC |c:5,t:8| Show InChI InChI=1S/C14H21NO4/c1-6-10-11(13(16)18-5)8(3)15-9(4)12(10)14(17)19-7-2/h10-11H,6-7H2,1-5H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.36E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes Curated by ChEMBL					Assay Description Displacement of [125]AB-MECA binding to human Adenosine A3 receptor expressed in HEK cells				J Med Chem 39: 2980-9 (1996) Article DOI: 10.1021/jm9600205 BindingDB Entry DOI: 10.7270/Q2833SQ6
					More data for this Ligand-Target Pair