BDBM50052676 CHEMBL115304::N-[3-(1H-Benzoimidazol-2-yl)-4-methyl-phenyl]-3-cyclohexyl-propionamide

SMILES: Cc1ccc(NC(=O)CCC2CCCCC2)cc1-c1nc2ccccc2[nH]1

InChI Key: InChIKey=LMAPJURKCARGLM-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL receptor (Homo sapiens (Human))	BDBM50052676 (CHEMBL115304 | N-[3-(1H-Benzoimidazol-2-yl)-4-meth...) Show SMILES Cc1ccc(NC(=O)CCC2CCCCC2)cc1-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C23H27N3O/c1-16-11-13-18(24-22(27)14-12-17-7-3-2-4-8-17)15-19(16)23-25-20-9-5-6-10-21(20)26-23/h5-6,9-11,13,15,17H,2-4,7-8,12,14H2,1H3,(H,24,27)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Concentration at which one-half of the maximum Low density lipoprotein receptor is upregulated in HepG2 cells				J Med Chem 39: 3343-56 (1996) Article DOI: 10.1021/jm960153q BindingDB Entry DOI: 10.7270/Q2FT8K4S
					More data for this Ligand-Target Pair