BDBM50052678 3-Cyclohexyl-N-[4-methyl-3-(5-methyl-1H-benzoimidazol-2-yl)-phenyl]-propionamide::CHEMBL114810

SMILES: Cc1ccc2nc([nH]c2c1)-c1cc(NC(=O)CCC2CCCCC2)ccc1C

InChI Key: InChIKey=HNXCLZZTQRVVGD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL receptor (Homo sapiens (Human))	BDBM50052678 (3-Cyclohexyl-N-[4-methyl-3-(5-methyl-1H-benzoimida...) Show SMILES Cc1ccc2nc([nH]c2c1)-c1cc(NC(=O)CCC2CCCCC2)ccc1C Show InChI InChI=1S/C24H29N3O/c1-16-8-12-21-22(14-16)27-24(26-21)20-15-19(11-9-17(20)2)25-23(28)13-10-18-6-4-3-5-7-18/h8-9,11-12,14-15,18H,3-7,10,13H2,1-2H3,(H,25,28)(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Concentration at which one-half of the maximum Low density lipoprotein receptor is upregulated in HepG2 cells				J Med Chem 39: 3343-56 (1996) Article DOI: 10.1021/jm960153q BindingDB Entry DOI: 10.7270/Q2FT8K4S
					More data for this Ligand-Target Pair