BDBM50052690 Acetic acid 4-[5-(3-cyclohexyl-propionylamino)-2-methyl-phenylcarbamoyl]-phenyl ester::CHEMBL112475

SMILES: CC(=O)Oc1ccc(cc1)C(=O)Nc1cc(NC(=O)CCC2CCCCC2)ccc1C

InChI Key: InChIKey=FOUFNSPRFFRKSN-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL receptor (Homo sapiens (Human))	BDBM50052690 (Acetic acid 4-[5-(3-cyclohexyl-propionylamino)-2-m...) Show SMILES CC(=O)Oc1ccc(cc1)C(=O)Nc1cc(NC(=O)CCC2CCCCC2)ccc1C Show InChI InChI=1S/C25H30N2O4/c1-17-8-12-21(26-24(29)15-9-19-6-4-3-5-7-19)16-23(17)27-25(30)20-10-13-22(14-11-20)31-18(2)28/h8,10-14,16,19H,3-7,9,15H2,1-2H3,(H,26,29)(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Concentration at which one-half of the maximum Low density lipoprotein receptor is upregulated in HepG2 cells				J Med Chem 39: 3343-56 (1996) Article DOI: 10.1021/jm960153q BindingDB Entry DOI: 10.7270/Q2FT8K4S
					More data for this Ligand-Target Pair