BDBM50052701 2-(4-Aminophenyl)-6-methoxybenzothiazole::4-(6-Methoxy-benzothiazol-2-yl)-phenylamine::CHEMBL92390::US10137210, Example 6-11CH3O-BTA-0
SMILES: COc1ccc2nc(sc2c1)-c1ccc(N)cc1
InChI Key: InChIKey=KLRFVKNLVPQVIN-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50052701 (2-(4-Aminophenyl)-6-methoxybenzothiazole | 4-(6-Me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (Human)) | BDBM50052701 (2-(4-Aminophenyl)-6-methoxybenzothiazole | 4-(6-Me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Pittsburgh—Of the Commonwealth System of Higher Education US Patent | Assay Description Initial competitive binding studies using [3H]CG and synthetic Aβ(1-40) were conducted to determine if CG, ThS and ThT bound to the same site(s)... | US Patent US10137210 (2018) BindingDB Entry DOI: 10.7270/Q21C1ZXS | |||||||||||
More data for this Ligand-Target Pair |