BDBM50052870 (R)-11-(2-Methoxy-phenyl)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline::CHEMBL333085
SMILES: COc1ccccc1-c1cccc2C[C@H]3N(C)CCc4cccc(c34)-c12
InChI Key: InChIKey=LEQQCMUWPDWHHF-OAQYLSRUSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50052870 ((R)-11-(2-Methoxy-phenyl)-6-methyl-5,6,6a,7-tetrah...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description In vitro displacement of [3H]-8-OH-DPAT binding to rat hippocampal 5-hydroxytryptamine 1A receptor | J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50052870 ((R)-11-(2-Methoxy-phenyl)-6-methyl-5,6,6a,7-tetrah...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Displacement of [3H]-raclopride fromd human Dopamine receptor D2A expressed in LtK- cells | J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (RAT) | BDBM50052870 ((R)-11-(2-Methoxy-phenyl)-6-methyl-5,6,6a,7-tetrah...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description In vitro displacement of [3H]-SCH-23,390 binding to rat striatal Dopamine receptor D1 | J Med Chem 39: 3503-13 (1996) Article DOI: 10.1021/jm960189i BindingDB Entry DOI: 10.7270/Q2T43S6S | |||||||||||
More data for this Ligand-Target Pair |