BDBM50053136 (1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indolizin-8-yloxy)-acetic acid methyl ester::CHEMBL121627

SMILES: COC(=O)COc1cccn2c(Cc3ccccc3-c3ccccc3)c(C)c(C(=O)C(N)=O)c12

InChI Key: InChIKey=DJGVPRFMZPMHEI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2 (Homo sapiens (Human))	BDBM50053136 ((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indo...) Show SMILES COC(=O)COc1cccn2c(Cc3ccccc3-c3ccccc3)c(C)c(C(=O)C(N)=O)c12 Show InChI InChI=1S/C27H24N2O5/c1-17-21(15-19-11-6-7-12-20(19)18-9-4-3-5-10-18)29-14-8-13-22(34-16-23(30)33-2)25(29)24(17)26(31)27(28)32/h3-14H,15-16H2,1-2H3,(H2,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.				J Med Chem 39: 3636-58 (1996) Article DOI: 10.1021/jm960395q BindingDB Entry DOI: 10.7270/Q2NC609M
					More data for this Ligand-Target Pair
Phospholipase A2 (Homo sapiens (Human))	BDBM50053136 ((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indo...) Show SMILES COC(=O)COc1cccn2c(Cc3ccccc3-c3ccccc3)c(C)c(C(=O)C(N)=O)c12 Show InChI InChI=1S/C27H24N2O5/c1-17-21(15-19-11-6-7-12-20(19)18-9-4-3-5-10-18)29-14-8-13-22(34-16-23(30)33-2)25(29)24(17)26(31)27(28)32/h3-14H,15-16H2,1-2H3,(H2,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Shionogi & Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).				J Med Chem 39: 3636-58 (1996) Article DOI: 10.1021/jm960395q BindingDB Entry DOI: 10.7270/Q2NC609M
					More data for this Ligand-Target Pair