BDBM50053297 1-{4-[2-(1H-Imidazol-4-yl)-ethoxy]-phenyl}-propan-1-one::CHEMBL340196

SMILES: CCC(=O)c1ccc(OCCc2cnc[nH]2)cc1

InChI Key: InChIKey=WVFFTJIGXOBNOU-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50053297 (1-{4-[2-(1H-Imidazol-4-yl)-ethoxy]-phenyl}-propan-...) Show SMILES CCC(=O)c1ccc(OCCc2cnc[nH]2)cc1 Show InChI InChI=1S/C14H16N2O2/c1-2-14(17)11-3-5-13(6-4-11)18-8-7-12-9-15-10-16-12/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-induced release of [3H]-histamine from rat cerebral cortex synaptosom...				J Med Chem 39: 3806-13 (1996) Article DOI: 10.1021/jm960138l BindingDB Entry DOI: 10.7270/Q20P0Z3F
					More data for this Ligand-Target Pair