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SMILES: NS(=O)(=O)c1cccc(c1)-c1n[nH]c2cc(NC(=O)c3cccs3)ccc12

InChI Key: InChIKey=HNRWRQXKGQOHEA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053324   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity protein kinase TTK


(Homo sapiens (Human))		BDBM50053324
PNG
(CHEMBL3330251)
Show SMILES NS(=O)(=O)c1cccc(c1)-c1n[nH]c2cc(NC(=O)c3cccs3)ccc12
Show InChI InChI=1S/C18H14N4O3S2/c19-27(24,25)13-4-1-3-11(9-13)17-14-7-6-12(10-15(14)21-22-17)20-18(23)16-5-2-8-26-16/h1-10H,(H,20,23)(H,21,22)(H2,19,24,25)
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Article
PubMed
n/an/a 4.30E+3n/an/an/an/an/an/a



University Health Network

Curated by ChEMBL


Assay Description
Inhibition of SUMO-tagged human TTK (1-275 residues) compound pre-incubated for 15 mins prior ATP addition by MBP-based assay

Bioorg Med Chem 22: 4968-97 (2014)


Article DOI: 10.1016/j.bmc.2014.06.027
BindingDB Entry DOI: 10.7270/Q2K35WB2
More data for this
Ligand-Target Pair