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SMILES: NS(=O)(=O)c1cccc(c1)-c1n[nH]c2ccc(cc12)C(=O)NC1(CC1)c1ccccc1

InChI Key: InChIKey=CSIVCMIGQNGADL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053358   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity protein kinase TTK


(Homo sapiens (Human))		BDBM50053358
PNG
(CHEMBL3330278)
Show SMILES NS(=O)(=O)c1cccc(c1)-c1n[nH]c2ccc(cc12)C(=O)NC1(CC1)c1ccccc1
Show InChI InChI=1S/C23H20N4O3S/c24-31(29,30)18-8-4-5-15(13-18)21-19-14-16(9-10-20(19)26-27-21)22(28)25-23(11-12-23)17-6-2-1-3-7-17/h1-10,13-14H,11-12H2,(H,25,28)(H,26,27)(H2,24,29,30)
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Similars
Article
PubMed
n/an/a 35n/an/an/an/an/an/a



University Health Network

Curated by ChEMBL


Assay Description
Inhibition of SUMO-tagged human TTK (1-275 residues) compound pre-incubated for 15 mins prior ATP addition by MBP-based assay

Bioorg Med Chem 22: 4968-97 (2014)


Article DOI: 10.1016/j.bmc.2014.06.027
BindingDB Entry DOI: 10.7270/Q2K35WB2
More data for this
Ligand-Target Pair