BDBM50053608 1N-amino(immino)methyl-3-chloroaniline::CHEMBL13823::N-(3-Chloro-phenyl)-guanidine::N-(3-chlorophenyl)guanidine

SMILES: [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1

InChI Key: InChIKey=DWLMIHRZURMFAQ-UHFFFAOYSA-N

Data: 7 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50053608   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Displacement of [3H]GR65630 from 5-HT3 receptor (unknown origin) expressed in mouse/rat NG108-15 cells after 30 mins by by liquid scintillation count...				Bioorg Med Chem Lett 23: 5945-8 (2013) Article DOI: 10.1016/j.bmcl.2013.08.072 BindingDB Entry DOI: 10.7270/Q2ZK5J31
					More data for this Ligand-Target Pair
Serotonin 3a (5-HT3a)/3b (5-HT3b)/3c (5-HT3c)/3d (5-HT3d)/3e (5-HT3e) receptor (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cells				J Med Chem 39: 4017-26 (1996) Article DOI: 10.1021/jm9603936 BindingDB Entry DOI: 10.7270/Q23F4NQT
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator/surface receptor (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.17E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description log1/Ki value was calculated against Urokinase-type plasminogen activator				J Med Chem 33: 2956-61 (1990) BindingDB Entry DOI: 10.7270/Q2GB24NB
					More data for this Ligand-Target Pair
Urokinase-type plasminogen activator (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition against Urokinase-type plasminogen activator				J Med Chem 33: 2956-61 (1990) BindingDB Entry DOI: 10.7270/Q2GB24NB
					More data for this Ligand-Target Pair
Trypsin (Bos taurus (bovine))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition against Trypsin				J Med Chem 33: 2956-61 (1990) BindingDB Entry DOI: 10.7270/Q2GB24NB
					More data for this Ligand-Target Pair
Trypsin I (Bos taurus (bovine))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition against Trypsin				J Med Chem 33: 2956-61 (1990) BindingDB Entry DOI: 10.7270/Q2GB24NB
					More data for this Ligand-Target Pair
Plasminogen (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	<1.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition against human plasmin was determined at 0.5 mM				J Med Chem 33: 2956-61 (1990) BindingDB Entry DOI: 10.7270/Q2GB24NB
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA. Curated by ChEMBL					Assay Description Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...				Bioorg Med Chem Lett 27: 4440-4445 (2017) Article DOI: 10.1016/j.bmcl.2017.08.008 BindingDB Entry DOI: 10.7270/Q24M970C
					More data for this Ligand-Target Pair
Solute carrier family 22 member 3 (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA. Curated by ChEMBL					Assay Description Inhibition of OCT3 (unknown origin)				Bioorg Med Chem Lett 27: 4440-4445 (2017) Article DOI: 10.1016/j.bmcl.2017.08.008 BindingDB Entry DOI: 10.7270/Q24M970C
					More data for this Ligand-Target Pair
Solute carrier family 22 member 2 (Homo sapiens (Human))	BDBM50053608 (1N-amino(immino)methyl-3-chloroaniline | CHEMBL138...) Show SMILES [#7]\[#6](-[#7])=[#7]\c1cccc(Cl)c1 Show InChI InChI=1S/C7H8ClN3/c8-5-2-1-3-6(4-5)11-7(9)10/h1-4H,(H4,9,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Department of Pharmaceutics, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA. Curated by ChEMBL					Assay Description Inhibition of human OCT2 expressed in HEK293 cells assessed as decrease in uptake of substrate [3H]MPP+ after 1 min by liquid scintillation counting ...				Bioorg Med Chem Lett 27: 4440-4445 (2017) Article DOI: 10.1016/j.bmcl.2017.08.008 BindingDB Entry DOI: 10.7270/Q24M970C
					More data for this Ligand-Target Pair