BDBM50053787 CHEMBL3356085

SMILES: O=C1CN2C(COc3ccc(NC4CNC4)cc23)=NN1

InChI Key: InChIKey=XKMTVGPOEMSDNX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50053787   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50053787 (CHEMBL3356085) Show SMILES O=C1CN2C(COc3ccc(NC4CNC4)cc23)=NN1 |c:20| Show InChI InChI=1S/C13H15N5O2/c19-13-6-18-10-3-8(15-9-4-14-5-9)1-2-11(10)20-7-12(18)16-17-13/h1-3,9,14-15H,4-7H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCalpha expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...				J Med Chem 58: 222-36 (2015) Article DOI: 10.1021/jm500669m BindingDB Entry DOI: 10.7270/Q22F7Q2Z
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50053787 (CHEMBL3356085) Show SMILES O=C1CN2C(COc3ccc(NC4CNC4)cc23)=NN1 |c:20| Show InChI InChI=1S/C13H15N5O2/c19-13-6-18-10-3-8(15-9-4-14-5-9)1-2-11(10)20-7-12(18)16-17-13/h1-3,9,14-15H,4-7H2,(H,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of human recombinant PKCtheta expressed in Sf21 cells using Bio-cdc peptide substrate and ATP after 60 mins by time-resolved fluorescence ...				J Med Chem 58: 222-36 (2015) Article DOI: 10.1021/jm500669m BindingDB Entry DOI: 10.7270/Q22F7Q2Z
					More data for this Ligand-Target Pair