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BDBM50053894 11-{[1-(9-Allyl-6-allylamino-9H-purin-2-yl)-piperidin-4-ylamino]-methyl}-5,11-dihydro-dibenzo[b,e]azepin-6-one::CHEMBL132782

SMILES: C=CCNc1nc(nc2n(CC=C)cnc12)N1CCC(CC1)NCC1c2ccccc2NC(=O)c2ccccc12

InChI Key: InChIKey=RHOHOPIORUHPME-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053894   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Voltage-gated L-type calcium channel


(Rattus norvegicus)		BDBM50053894
PNG
(11-{[1-(9-Allyl-6-allylamino-9H-purin-2-yl)-piperi...)
Show SMILES C=CCNc1nc(nc2n(CC=C)cnc12)N1CCC(CC1)NCC1c2ccccc2NC(=O)c2ccccc12
Show InChI InChI=1S/C31H34N8O/c1-3-15-32-28-27-29(39(16-4-2)20-34-27)37-31(36-28)38-17-13-21(14-18-38)33-19-25-22-9-5-6-11-24(22)30(40)35-26-12-8-7-10-23(25)26/h3-12,20-21,25,33H,1-2,13-19H2,(H,35,40)(H,32,36,37)
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Article
PubMed
 3.70E+3n/an/an/an/an/an/an/an/a



Institut de Recherches Servier

Curated by ChEMBL


Assay Description
Inhibition of [3H]-D-888 binding to L-type [Ca2+] channel of membranes from rat skeletal muscle

J Med Chem 39: 4099-108 (1996)


Article DOI: 10.1021/jm960361i
BindingDB Entry DOI: 10.7270/Q2Q81C52
More data for this
Ligand-Target Pair