BDBM50054234 6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-phenyl)-[1,3,5]triazine-2,4-diamine::CHEMBL77527

SMILES: CN(CCc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1

InChI Key: InChIKey=YJXAVYAIPCMZGR-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054234   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054234 (6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-pheny...) Show SMILES CN(CCc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C22H27N5/c1-15-13-16(2)20(17(3)14-15)25-21-23-18(4)24-22(26-21)27(5)12-11-19-9-7-6-8-10-19/h6-10,13-14H,11-12H2,1-5H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054234 (6,N-Dimethyl-N-phenethyl-N'-(2,4,6-trimethyl-pheny...) Show SMILES CN(CCc1ccccc1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 Show InChI InChI=1S/C22H27N5/c1-15-13-16(2)20(17(3)14-15)25-21-23-18(4)24-22(26-21)27(5)12-11-19-9-7-6-8-10-19/h6-10,13-14H,11-12H2,1-5H3,(H,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair