BDBM50054241 6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-trimethyl-phenyl)-[1,3,5]triazine-2,4-diamine::CHEMBL78271

SMILES: Cc1cc(C)c(Nc2nc(C)nc(NCc3ccc(cc3)C(F)(F)F)n2)c(C)c1

InChI Key: InChIKey=RXJUNCIHCQGQGJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054241   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054241 (6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-tr...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(NCc3ccc(cc3)C(F)(F)F)n2)c(C)c1 Show InChI InChI=1S/C21H22F3N5/c1-12-9-13(2)18(14(3)10-12)28-20-27-15(4)26-19(29-20)25-11-16-5-7-17(8-6-16)21(22,23)24/h5-10H,11H2,1-4H3,(H2,25,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Wollongong Curated by ChEMBL					Assay Description Inhibition of [125I]-CRH binding to human Corticotropin releasing factor receptor 1.				J Med Chem 42: 2351-7 (1999) Article DOI: 10.1021/jm9900117 BindingDB Entry DOI: 10.7270/Q2WS8SF0
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50054241 (6-Methyl-N-(4-trifluoromethyl-benzyl)-N'-(2,4,6-tr...) Show SMILES Cc1cc(C)c(Nc2nc(C)nc(NCc3ccc(cc3)C(F)(F)F)n2)c(C)c1 Show InChI InChI=1S/C21H22F3N5/c1-12-9-13(2)18(14(3)10-12)28-20-27-15(4)26-19(29-20)25-11-16-5-7-17(8-6-16)21(22,23)24/h5-10H,11H2,1-4H3,(H2,25,26,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Inhibition of [125I]-CRF binding to human corticotropin releasing factor receptor 1				J Med Chem 39: 4354-7 (1996) Article DOI: 10.1021/jm960148m BindingDB Entry DOI: 10.7270/Q2DR2TK7
					More data for this Ligand-Target Pair