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BDBM50054462 CHEMBL3323076

SMILES: CCOC(=O)c1cncc(c1)[C@@]1(N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccc(F)cc1)c1cnn(C)c1

InChI Key:

Data: 4 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054462
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50054462 (CHEMBL3323076) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]SS-14 from human SSTR3 expressed in CHO cells by TopCount analyzer				ACS Med Chem Lett 5: 748-53 (2014) Article DOI: 10.1021/ml500028c BindingDB Entry DOI: 10.7270/Q2NV9KXP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Somatostatin receptor type 3 (Homo sapiens (Human))	BDBM50054462 (CHEMBL3323076) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysis				ACS Med Chem Lett 5: 748-53 (2014) Article DOI: 10.1021/ml500028c BindingDB Entry DOI: 10.7270/Q2NV9KXP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Somatostatin receptor 3 (MOUSE)	BDBM50054462 (CHEMBL3323076) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at mouse SSTR3 expressed in CHO cells assessed as cAMP level by fluorescence analysis				ACS Med Chem Lett 5: 748-53 (2014) Article DOI: 10.1021/ml500028c BindingDB Entry DOI: 10.7270/Q2NV9KXP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50054462 (CHEMBL3323076) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human ERG by MK-499 displacement binding analysis				ACS Med Chem Lett 5: 748-53 (2014) Article DOI: 10.1021/ml500028c BindingDB Entry DOI: 10.7270/Q2NV9KXP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair