BDBM50054548 (Z)-N-(4-Bromo-phenyl)-2-cyano-3-cyclopropyl-3-hydroxy-acrylamide::CHEMBL142214

SMILES: Brc1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1

InChI Key: InChIKey=WVQOCQNOMMJAIS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50054548   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (Mus musculus)	BDBM50054548 ((Z)-N-(4-Bromo-phenyl)-2-cyano-3-cyclopropyl-3-hyd...) Show SMILES Brc1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1 Show InChI InChI=1S/C13H11BrN2O2/c14-9-3-5-10(6-4-9)16-13(18)11(7-15)12(17)8-1-2-8/h3-6,8,11H,1-2H2,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibitory concentration tested on enzyme dihydroorotate dehydrogenase in mouse				J Med Chem 39: 4608-21 (1996) Article DOI: 10.1021/jm9604437 BindingDB Entry DOI: 10.7270/Q20G3KSX
					More data for this Ligand-Target Pair
Dihydroorotate Dehydrogenase (DHODH) (Rattus norvegicus (rat))	BDBM50054548 ((Z)-N-(4-Bromo-phenyl)-2-cyano-3-cyclopropyl-3-hyd...) Show SMILES Brc1ccc(NC(=O)C(C#N)C(=O)C2CC2)cc1 Show InChI InChI=1S/C13H11BrN2O2/c14-9-3-5-10(6-4-9)16-13(18)11(7-15)12(17)8-1-2-8/h3-6,8,11H,1-2H2,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Marion Roussel Curated by ChEMBL					Assay Description Inhibitory concentration tested against enzyme dihydroorotate dehydrogenase in rat				J Med Chem 39: 4608-21 (1996) Article DOI: 10.1021/jm9604437 BindingDB Entry DOI: 10.7270/Q20G3KSX
					More data for this Ligand-Target Pair